Tanzer M, Kantor S, Bobyn J D
Division of Orthopaedic Surgery, McGill University, Montreal, Que, Canada.
J Orthop Res. 2001 Mar;19(2):195-9. doi: 10.1016/S0736-0266(00)00034-6.
An in vivo study was designed to determine if non-invasive low intensity ultrasound could enhance bone growth into porous intramedullary implants. Fully porous intramedullary rods were implanted bilaterally into the ulnae of six dogs. In each dog, one ulna served as a control and the other was treated with 20 min of daily ultrasound stimulation for 6 consecutive weeks. Analysis of serial transverse sections indicated an average of 119% more bone growth into the ultrasound-treated implants compared with the contralateral controls (P < 0.001). In each of the 6 dogs, there was a significantly greater amount of bone ingrowth on the ultrasound-stimulated side. These data indicate a clear potential for externally applied ultrasound therapy to augment biological fixation.
一项体内研究旨在确定非侵入性低强度超声是否能促进骨长入多孔髓内植入物。将完全多孔的髓内棒双侧植入6只狗的尺骨。在每只狗中，一根尺骨作为对照，另一根尺骨连续6周每天接受20分钟的超声刺激。对连续横断面的分析表明，与对侧对照相比，超声治疗的植入物的骨生长平均多119%（P<0.001）。在6只狗中的每只狗身上，超声刺激侧的骨长入量都显著更多。这些数据表明，外部应用超声治疗增强生物固定具有明显的潜力。
