铑（I）催化的N-芳基三氟乙酰亚胺酰氯与炔烃的偶联环化反应：氟化喹啉的一锅法合成
Rh(I)-catalyzed coupling cyclization of N-aryl trifluoroacetimidoyl chlorides with alkynes: one-pot synthesis of fluorinated quinolines.
作者信息
Amii H, Kishikawa Y, Uneyama K
机构信息
Department of Applied Chemistry, Faculty of Engineering, Okayama University 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.
出版信息
Org Lett. 2001 Apr 19;3(8):1109-12. doi: 10.1021/ol006936u.
PMID:11348171
Abstract
[reaction: see text]. Rh(I) complexes were found to catalyze the coupling cyclization of N-aryl trifluoroacetimidoyl chlorides with alkynes to afford 2-trifluoromethylated quinolines in good yields. Various alkynes were applied to this cyclization coupling with regioselectivity.
摘要
[反应：见正文]。发现铑（I）配合物可催化N-芳基三氟乙酰亚胺酰氯与炔烃的偶联环化反应，以良好的产率得到2-三氟甲基喹啉。各种炔烃被用于这种具有区域选择性的环化偶联反应。
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