Jankowska E
Department of Physiology, Göteborg University, Box 432, 405 30 Göteborg, Sweden.
J Physiol. 2001 May 15;533(Pt 1):31-40. doi: 10.1111/j.1469-7793.2001.0031b.x.
This review focuses on the flexibility of operation of spinal interneuronal networks and their multifunctional character in mammals. It concerns, in particular, two ways in which spinal interneuronal networks may be functionally reorganised, namely by modulating the synaptic actions of primary afferents by monoamines and by GABAergic presynaptic inhibition. The evidence will be reviewed for topographical and target-related differences in modulatory effects in various interneuronal networks and these will be related to differences in the intrinsic properties of different functional types of interneurones in these networks and to the role played by them.
本综述聚焦于哺乳动物脊髓中间神经元网络的操作灵活性及其多功能特性。尤其涉及脊髓中间神经元网络可能在功能上重新组织的两种方式,即通过单胺调节初级传入神经的突触作用以及通过GABA能突触前抑制。将综述关于各种中间神经元网络中调节作用的拓扑学和靶点相关差异的证据,这些差异将与这些网络中不同功能类型中间神经元的内在特性差异以及它们所起的作用相关联。