[来自1906年罗氏青霉（Penicillium roquefortii Thom）真菌的微量生物碱]

[Minor alkaloids from the fungus Penicillium roquefortii Thom 1906].

作者信息

Vinokurova N G, Boĭchenko D M, Baskunov B P, Zelenkova N F, Vepritskaia I G, Arinbasarov M U, Reshetilova T A

机构信息

Skryabin Institute of Biochemistry and Physiology of Microorganism RAS, Pushchino, Moscow Region, 142290.

出版信息

Prikl Biokhim Mikrobiol. 2001 Mar-Apr;37(2):209-13.

PMID:11357427

Abstract

New spatial of clavine alkaloids, distinguished by low chromatographical mobility, have been isolated from the collection and mutant strain of Penicillium roquefortii, in addition to alkaloids roquefortine, 3,12-dihydroroquefortine, isofumigaclavines A and B, festuclavine, and chanoclavine-I, characteristic of this fungal species. In has been shown that the collection strain produces isomers of agroclavine and epoxyagroclavine, and the mutant strain produces isomers of fumigaclavines A and B, festuclavine, and chanoclavine.

摘要

除了该真菌物种特有的罗克福汀生物碱、3,12-二氢罗克福汀、异烟曲霉色氨酸A和B、费斯曲霉素以及浅蓝菌素-I之外，还从罗克福青霉的菌株和突变菌株中分离出了色谱迁移率较低的新麦角碱空间异构体。已表明该菌株产生农吉利麦角碱和环氧农吉利麦角碱的异构体，而突变菌株产生烟曲霉色氨酸A和B、费斯曲霉素以及浅蓝菌素的异构体。