调Q开关钕：钇铝石榴石激光：通过非剥脱性皮肤重塑改善皱纹。
Q-switched Nd:YAG laser: rhytid improvement by non-ablative dermal remodeling.
作者信息
Goldberg D J, Silapunt S
机构信息
New Jersey Medical School, Newark, NJ, USA.
出版信息
J Cutan Laser Ther. 2000 Sep;2(3):157-60. doi: 10.1080/14628830050516425.
BACKGROUND
The Q-switched Nd:YAG laser has been used for a variety of dermatologic indications including tattoo and hair removal, as well as vascular and pigmented lesion treatment. Previous studies have suggested that this laser may also be safe and effective in the non-ablative treatment of rhytids.
OBJECTIVES
The purpose of this study was to evaluate the safety and efficacy of the Q-switched Nd:YAG laser in the non-ablative dermal remodeling of facial rhytids.
METHODS
Eight subjects were treated at 3 monthly intervals with a Q-switched Nd:YAG laser. Two passes with fluences of 7 J/cm2 and a 3-mm spot size were utilized. Clinical improvement and adverse effects were assessed 3 months after the last treatment.
RESULTS
Six of the eight subjects showed clinical improvement as assessed by an independent observer. No pigmentary changes, erythema, or scarring were observed at the end of the study.
CONCLUSION
The Q-switched Nd:YAG laser may be used for the non-ablative treatment of facial rhytids.
背景
调Q开关钕：钇铝石榴石激光已用于多种皮肤科适应症，包括纹身去除、脱毛以及血管性和色素性病变的治疗。先前的研究表明，这种激光在非剥脱性治疗皱纹方面可能也是安全有效的。
目的
本研究的目的是评估调Q开关钕：钇铝石榴石激光对面部皱纹进行非剥脱性真皮重塑的安全性和有效性。
方法
8名受试者每隔3个月接受一次调Q开关钕：钇铝石榴石激光治疗。采用能量密度为7 J/cm²、光斑大小为3 mm的两次照射。在最后一次治疗3个月后评估临床改善情况和不良反应。
结果
8名受试者中有6名经独立观察者评估显示有临床改善。研究结束时未观察到色素沉着改变、红斑或瘢痕形成。
结论
调Q开关钕：钇铝石榴石激光可用于面部皱纹的非剥脱性治疗。
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