年龄对事件相关电位晚期成分及反应时间的影响。

The effects of age on late components of the ERP and reaction time.

作者信息

Bahramali H, Gordon E, Lagopoulos J, Lim C L, Li W, Leslie J, Wright J

机构信息

Cognitive Neuroscience Unit, Department of Psychological Medicine, Westmead Hospital, University of Sydney, Australia.

出版信息

Exp Aging Res. 1999 Jan-Mar;25(1):69-80. doi: 10.1080/036107399244147.

DOI:10.1080/036107399244147

PMID:11370110

Abstract

The effects of age on late component (N100, P200, N200, and P300) event-related potentials (ERP) and reaction time (RT) were investigated in 50 normal subjects, 18 to 70 years of age. A conventional auditory oddball paradigm was employed. An equal number of subjects, as well as an equal number of males and females, were examined in each decade. There were no significant associations found between ERP amplitude and age. A significant positive correlation was found between age and N200/P300 latency. There were no significant effects of age on RT in the overall group. However, females had slower RT and decreased P200 and N200 amplitude as compared with males. Moreover, males had significant correlations between N200 latency and RT, whereas females showed significant correlations between P300 amplitude and RT. ERP/RT effects should be further explicated between gender, as well as across age.

摘要

在50名年龄在18至70岁的正常受试者中，研究了年龄对晚期成分（N100、P200、N200和P300）事件相关电位（ERP）和反应时间（RT）的影响。采用了传统的听觉oddball范式。每个十年检查的受试者数量相等，男性和女性的数量也相等。未发现ERP波幅与年龄之间存在显著关联。发现年龄与N200/P300潜伏期之间存在显著正相关。在整个组中，年龄对反应时间没有显著影响。然而，与男性相比，女性的反应时间较慢，P200和N200波幅降低。此外，男性的N200潜伏期与反应时间之间存在显著相关性，而女性的P300波幅与反应时间之间存在显著相关性。ERP/RT效应应在性别之间以及不同年龄之间进一步阐明。