Bourisly Ali K, Shuaib Ali
Biomedical Engineering Unit, Department of Physiology, Faculty of Medicine, Kuwait University, Kuwait city, Kuwait.
Transl Neurosci. 2018 Jun 22;9:61-66. doi: 10.1515/tnsci-2018-0011. eCollection 2018.
Age-related effects were studied in 14 younger (M = 34 years) and 14 (M = 47 years) older healthy participants. Event-related potential (ERP) recording was done using a 256-channel EEG system. Results indicated that ERP is affected by advanced age. There was a significant difference in P200 mean latency between the younger participants and older participants for the target (low-probability) stimuli, but no such significance was evident for the P200 mean latency during the presentation of the standard (high-probability) stimuli. As for the P200 mean peak amplitude, the results for the target (low-probability) stimuli did show a significant difference between the two age groups, while the results for the standard (high-probability) stimuli did not show any significant difference between the two age groups. The results of this study are explained in light of aging effects on attentional recruitment and frontal lobe intactness.
在14名较年轻（平均年龄34岁）和14名较年长（平均年龄47岁）的健康参与者中研究了年龄相关效应。使用256通道脑电图系统进行事件相关电位（ERP）记录。结果表明ERP受高龄影响。对于目标（低概率）刺激，年轻参与者和年长参与者之间的P200平均潜伏期存在显著差异，但在呈现标准（高概率）刺激期间，P200平均潜伏期没有明显差异。至于P200平均峰值幅度，目标（低概率）刺激的结果在两个年龄组之间确实显示出显著差异，而标准（高概率）刺激的结果在两个年龄组之间没有显示出任何显著差异。根据衰老对注意力募集和额叶完整性的影响来解释本研究结果。
