各种血清群链球菌对克林霉素和林可霉素的敏感性。
Susceptibility of various serogroups of streptococci to clindamycin and lincomycin.
作者信息
Karchmer A W, Moellering R C, Watson B K
出版信息
Antimicrob Agents Chemother. 1975 Feb;7(2):164-7. doi: 10.1128/AAC.7.2.164.
Abstract
The minimal inhibitory concentration of lincomycin and clindamycin for a large number of strains from multiple serogroups of streptococci was determined. The median minimal inhibitory concentration for streptococci from groups A, B, C, F, G, H, L, and M and nongroupable organisms ranged from 0.02 to 0.39 mug of lincomycin per ml and from </=0.01 to 0.09 mug of clindamycin per ml. Among the group D strains, Streptococcus faecium and Streptococcus faecalis were resistant to lincomycin and clindamycin, whereas Streptococcus bovis and four American strains of Streptococcus durans resembled nongroup D isolates in their susceptibility to these agents. Occasional strains of nongroup D streptococci were highly resistant to lincomycin and clindamycin.
摘要
测定了林可霉素和克林霉素对来自多个血清群链球菌的大量菌株的最低抑菌浓度。A、B、C、F、G、H、L和M群链球菌以及不可分组菌的林可霉素最低抑菌浓度中位数为每毫升0.02至0.39微克，克林霉素最低抑菌浓度中位数为每毫升≤0.01至0.09微克。在D群菌株中，粪肠球菌和屎肠球菌对林可霉素和克林霉素耐药，而牛链球菌和4株美国杜兰链球菌对这些药物的敏感性与非D群分离株相似。偶尔有非D群链球菌菌株对林可霉素和克林霉素高度耐药。
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