实验性风疹感染中的细胞介导免疫
Cell mediated immunity in experimental rubella infections.
作者信息
Cappel R
出版信息
Arch Virol. 1975;47(4):375-9. doi: 10.1007/BF01347979.
PMID:1137503
Abstract
Antibody and cell-bound immune response were assessed in rabbits inoculated by the intravenous route with Cenedehill or with wild rubella virus. Our results suggest that wild or attenuated live rubella virus induce a transient unresponsiveness of the lymphocytes to PHA stimulation in vitro and suggest also that this immunosuppression was due to the persistence of rubella virus in the lymphocytes.
摘要
通过静脉途径用Cenedehill或野生风疹病毒接种兔子后，评估了抗体和细胞结合免疫反应。我们的结果表明，野生或减毒活风疹病毒在体外诱导淋巴细胞对PHA刺激产生短暂的无反应性，并且还表明这种免疫抑制是由于风疹病毒在淋巴细胞中的持续存在。
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