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实验性风疹感染中的细胞介导免疫

Cell mediated immunity in experimental rubella infections.

作者信息

Cappel R

出版信息

Arch Virol. 1975;47(4):375-9. doi: 10.1007/BF01347979.

DOI:10.1007/BF01347979
PMID:1137503
Abstract

Antibody and cell-bound immune response were assessed in rabbits inoculated by the intravenous route with Cenedehill or with wild rubella virus. Our results suggest that wild or attenuated live rubella virus induce a transient unresponsiveness of the lymphocytes to PHA stimulation in vitro and suggest also that this immunosuppression was due to the persistence of rubella virus in the lymphocytes.

摘要

通过静脉途径用Cenedehill或野生风疹病毒接种兔子后，评估了抗体和细胞结合免疫反应。我们的结果表明，野生或减毒活风疹病毒在体外诱导淋巴细胞对PHA刺激产生短暂的无反应性，并且还表明这种免疫抑制是由于风疹病毒在淋巴细胞中的持续存在。

相似文献

1
Cell mediated immunity in experimental rubella infections.实验性风疹感染中的细胞介导免疫
Arch Virol. 1975;47(4):375-9. doi: 10.1007/BF01347979.
2
Efficacy and immune response to rubella subunits vaccines.
Arch Virol. 1976;50(3):207-13. doi: 10.1007/BF01320574.
3
Suppression of the response of lymphocytes to phytohemagglutinin in rubella.风疹中淋巴细胞对植物血凝素反应的抑制
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4
Persistent rubella infection and rubella-associated arthritis.持续性风疹感染与风疹相关性关节炎。
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Genetic stability in humans of the rabbit immunogenic marker of Cendehill rubella vaccine virus.风疹疫苗病毒Cendehill株兔免疫原性标记在人体中的遗传稳定性。
Arch Gesamte Virusforsch. 1973;43(1):135-43. doi: 10.1007/BF01249356.
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Impaired in vitro cell-mediated immunity to rubella virus during pregnancy.孕期风疹病毒体外细胞介导免疫受损。
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Study of the lymphocyte in vitro response to rubella antigen and phytohemagglutinin by a whole blood method.采用全血法研究淋巴细胞对风疹抗原和植物血凝素的体外反应。
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引用本文的文献

1
Efficacy and immune response to rubella subunits vaccines.
Arch Virol. 1976;50(3):207-13. doi: 10.1007/BF01320574.
2
Immunosuppression and isolation of rubella virus from human lymphocytes after vaccination with two rubella vaccines.接种两种风疹疫苗后人体淋巴细胞中风疹病毒的免疫抑制与分离
Infect Immun. 1979 Jul;25(1):352-6. doi: 10.1128/iai.25.1.352-356.1979.
3
Components of parainfluenza-3 virus, SLP-strain, reacting in assays of cell-mediated immunity in cattle.
Arch Virol. 1977;53(4):323-33. doi: 10.1007/BF01315631.
4

本文引用的文献

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A micro tissue culture test for the titration and neutralization of rubella virus.
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Immune competence in congenital rubella: lymphocyte transformation, delayed hypersensitivity, and response to vaccination.先天性风疹的免疫能力：淋巴细胞转化、迟发型超敏反应及对疫苗接种的反应。
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Experimental immunosuppression induced by herpes simplex virus.单纯疱疹病毒诱导的实验性免疫抑制
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Progressive rubella panencephalitis: immunovirological studies and results of isoprinosine therapy.进行性风疹全脑炎：免疫病毒学研究及异丙肌苷治疗结果
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Effect of HPV-80 rubella vaccine on the tuberculin reaction.人乳头瘤病毒80型风疹疫苗对结核菌素反应的影响。
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Lymphoblast proliferation and humoral antibody response after rubella vaccination.风疹疫苗接种后的淋巴细胞增殖和体液抗体反应。
Clin Exp Immunol. 1973 Oct;15(2):193-202.
8
Evidence of suppressor cell activity in spleens of mice bearing primary tumors induced by Moloney sarcoma virus.携带莫洛尼肉瘤病毒诱导的原发性肿瘤的小鼠脾脏中抑制细胞活性的证据。
J Exp Med. 1974 Jun 1;139(6):1473-87. doi: 10.1084/jem.139.6.1473.
9
The splenic suppressor cell. I. Activity of thymus-dependent adherent cells: changes with age and stress.脾抑制细胞。I. 胸腺依赖性黏附细胞的活性：随年龄和应激的变化
J Immunol. 1974 Jul;113(1):127-39.
10
A micro-mixed leukocyte culture technique using whole blood.一种使用全血的微量混合白细胞培养技术。
Int Arch Allergy Appl Immunol. 1972;43(5):759-65. doi: 10.1159/000230891.