Abbadi S, Rashed H G, Morlock G P, Woodley C L, El Shanawy O, Cooksey R C
Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
J Clin Microbiol. 2001 Jun;39(6):2330-4. doi: 10.1128/JCM.39.6.2330-2334.2001.
We evaluated 25 Mycobacterium tuberculosis isolates from patients at a major Egyptian reference hospital in Assiut, Egypt, who had been treated for at least 1 year for tuberculosis. Typing patterns (IS6110) were diverse, and multidrug resistance was found among 11 (44%) of the isolates. Mutations associated with antimicrobial drug resistance were found in rpoB, katG, rpsL, and embB in the resistant isolates.
我们对来自埃及阿斯尤特一家主要埃及参考医院的25株结核分枝杆菌分离株进行了评估,这些患者已接受至少1年的结核病治疗。分型模式(IS6110)多种多样,在11株(44%)分离株中发现了多重耐药性。在耐药分离株的rpoB、katG、rpsL和embB中发现了与抗菌药物耐药性相关的突变。