Buzzi G, Cirignotta F
Sleep Medicine Unit, Department of Neurology, S. Orsola-Malpighi Hospital, University of Bologna, Italy.
Sleep Res Online. 2000;3(2):61-6.
Isolated Sleep Paralysis (SP) occurs at least once in a lifetime in 40-50% of normal subjects, while as a chronic complaint it is an uncommon and scarcely known disorder. A series of messages written by subjects who experienced at least one episode of SP, containing more or less detailed descriptions of this disorder, were collected from the Sleep Web site of the University of California in Los Angeles between January 1996 and July 1998. Two hundred and sixty-four messages fulfilling the International Classification of Sleep Disorders (ICSD) (Thorpy, 1990) minimal criteria for SP were analyzed. A wide spectrum of severity was evident, with a frequency of episodes ranging from one in a lifetime to almost every night, and a variety of emotional and hallucinatory experiences associated with SP episodes were reported. Clinical similarities between the recurrent form of isolated SP and channelopathies (in particular, periodic paralyses) are discussed. An activation of limbic system structures is suggested in order to explain some of the most common subjective experiences associated with SP.
孤立性睡眠麻痹（SP）在40%至50%的正常受试者一生中至少会出现一次，而作为一种慢性主诉，它是一种罕见且鲜为人知的疾病。1996年1月至1998年7月期间，从洛杉矶加利福尼亚大学睡眠网站收集了一系列由经历过至少一次SP发作的受试者撰写的信息，其中或多或少包含了对这种疾病的详细描述。对264条符合国际睡眠障碍分类（ICSD）（Thorpy，1990）中SP最低标准的信息进行了分析。病情严重程度范围很广，发作频率从一生一次到几乎每晚发作，并且报告了与SP发作相关的各种情绪和幻觉体验。文中讨论了复发性孤立性SP与通道病（特别是周期性麻痹）之间的临床相似性。为了解释与SP相关的一些最常见主观体验，文中提出了边缘系统结构的激活。
