Nelson S D, Pollet J E
Tissue Antigens. 1975 Feb;5(1):38-40. doi: 10.1111/j.1399-0039.1975.tb00524.x.
HL-A phenotypes were determined in 60 patients with primary thyrotoxicosis and in 60 age-sex matched controls living in the same region in order to establish the frequencies of ten HL-A antigens in the two populations. HL-A1 was present in 28 patients and 18 controls (X2 equals 2;86, P greater than 0,05); HL-A13 was present in eigth patients and only one control (X2 equals 4.32, 0.05 greater than P greater than 0.025). These findings suggest that HL-A phenotypes may be of value in studies on the aetiology of primary thyrotoxicosis. The statistical significance of these results is discussed as these findings may be due to chance deviations.
对60例原发性甲状腺毒症患者及60例居住在同一地区、年龄和性别匹配的对照者进行了HL - A表型测定，以确定这两种人群中10种HL - A抗原的频率。28例患者和18例对照者存在HL - A1（X² = 2.86，P＞0.05）；8例患者和仅1例对照者存在HL - A13（X² = 4.32，0.05＞P＞0.025）。这些发现提示HL - A表型在原发性甲状腺毒症病因学研究中可能具有价值。由于这些发现可能是偶然偏差所致，因此对这些结果的统计学意义进行了讨论。
