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霍奇金淋巴瘤的罕见临床体征:眼部受累。

Rare Clinical Sign of Hodgkin's Lymphoma: Ocular Involvement.

作者信息

Ayhan Ziya, Yıldırım Karabağ Revan, Alacacıoğlu İnci, Kaynak Süleyman, Koçak Nilüfer

机构信息

Dokuz Eylül University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey.

Manisa State Hospital, Ophthalmology Clinic, Manisa, Turkey.

出版信息

Turk J Ophthalmol. 2017 Apr;47(2):110-112. doi: 10.4274/tjo.92609. Epub 2017 Apr 1.

Abstract

Bilateral non-granulomatous anterior uveitis with left vitritis and macular edema were detected in a 19-year-old woman presenting with blurred vision in her left eye. Light microscopic study of the pathologic mediastinal lymph node that was detected via contrast computed tomography imaging during etiologic study revealed nodular sclerosing and mixed cellularity Hodgkin's lymphoma (HL). Ocular findings completely resolved with adriablastin, bleomycin, vinblastine, dacarbazine chemotherapy treatment. Herein, it is emphasized that HL should be remembered as one of the differential diagnoses in patients with ocular inflammatory pathologies such as uveitis and vasculitis. The ocular findings of HL are discussed.

摘要

一名19岁女性因左眼视力模糊就诊,检查发现双侧非肉芽肿性前葡萄膜炎伴左眼玻璃体炎和黄斑水肿。在病因学研究期间,通过对比计算机断层扫描成像检测到的病理性纵隔淋巴结的光镜检查显示为结节硬化型和混合细胞型霍奇金淋巴瘤(HL)。经阿霉素、博来霉素、长春花碱、达卡巴嗪化疗后,眼部症状完全缓解。在此强调,HL应作为葡萄膜炎和血管炎等眼部炎症性疾病患者的鉴别诊断之一予以考虑。本文讨论了HL的眼部表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abda/5384116/2aea9b6a643c/TJO-47-110-g1.jpg

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