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提高发育性语言障碍筛查的阳性预测值。

Improving the positive predictive value of screening for developmental language disorder.

作者信息

Klee T, Pearce K, Carson D K

机构信息

University of Newcastle upon Tyne, England.

出版信息

J Speech Lang Hear Res. 2000 Aug;43(4):821-33. doi: 10.1044/jslhr.4304.821.

DOI:10.1044/jslhr.4304.821
PMID:11386471
Abstract

In a previous study, we reported the results of an early language screening program in which 306 children were screened using a parent-report questionnaire sent through the mail (Klee et al., 1998). A sample of the children screened were given clinical evaluations within a month of screening (n = 64) and again 1 year later (n = 36). Although the screening program correctly identified 91% of 2-year-olds with language delay, it produced a large number of over-referrals. In the present study we examine a revised screening criterion designed to reduce the number of false positives. The revised criterion generated fewer positive screens overall than the original and resulted in improved specificity (96% vs. 87%) and positive predictive value (77% vs. 51%), while maintaining the high sensitivity (91%) and negative predictive value (98%) of the original criterion. We also propose a screening score based on the new criterion, designed to inform the process of deciding which children to bring in for further evaluation.

摘要

在之前的一项研究中,我们报告了一项早期语言筛查项目的结果,该项目中306名儿童通过邮寄的家长报告问卷进行筛查(克莱等人,1998年)。被筛查儿童的一个样本在筛查后一个月内接受了临床评估(n = 64),并在一年后再次接受评估(n = 36)。尽管筛查项目正确识别了91%有语言延迟的2岁儿童,但它产生了大量过度转诊。在本研究中,我们检验了一项旨在减少假阳性数量的修订筛查标准。修订后的标准总体上产生的阳性筛查结果比原来少,特异性得到提高(96%对87%)和阳性预测值提高(77%对51%),同时保持了原标准的高敏感性(91%)和阴性预测值(98%)。我们还基于新标准提出了一个筛查分数,旨在为决定带哪些儿童进行进一步评估的过程提供参考。

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