Sugita M, Izuno T, Tatemichi M, Otahara Y
Department of Environmental and Occupational Health, Toho University School of Medicine, Tokyo, Japan.
J Epidemiol. 2001 Mar;11(2):87-94. doi: 10.2188/jea.11.87.
Many epidemiologic studies on the relationship between smoking and Parkinson's disease (PD) have been conducted. Morens et al. reviewed many articles in the study field and concluded that smoking is inversely associated with the risk of PD. In the present study, the object is to obtain summarized risk estimates of the relationship from the published articles using meta-analysis. Summarized risk estimates on the relationship between smoking and PD were found to be about 0.5 with statistical significance in meta-analysis. Therefore, the result that smoking is inversely associated with the risk of PD is appropriate.
已经开展了许多关于吸烟与帕金森病（PD）关系的流行病学研究。莫伦斯等人回顾了该研究领域的许多文章，并得出结论：吸烟与帕金森病风险呈负相关。在本研究中，目的是通过荟萃分析从已发表的文章中获得该关系的汇总风险估计值。在荟萃分析中发现，吸烟与帕金森病关系的汇总风险估计值约为0.5，具有统计学意义。因此，吸烟与帕金森病风险呈负相关这一结果是合理的。
