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地榆根中的三萜糖苷。

Triterpene glycosides from the roots of Sanguisorba officinalis.

作者信息

Mimaki Y, Fukushima M, Yokosuka A, Sashida Y, Furuya S, Sakagami H

机构信息

Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1, Horinouchi, Hachioji, Tokyo 192-0392, Japan.

出版信息

Phytochemistry. 2001 Jul;57(5):773-9. doi: 10.1016/s0031-9422(01)00083-8.

Abstract

Five triterpene glycosides were isolated from the MeOH extract of Sanguisorba officinalis (Rosaceae) roots, as confirmed by detailed analysis of their 1H, 13C, and two-dimensional NMR data, and by the results of hydrolytic cleavage. Three known triterpenes and six known triterpene glycosides were also isolated and identified. The isolated compounds were evaluated for their cytotoxic activities against HSC-2 cells and HGF.

摘要

从蔷薇科地榆属植物地榆根部的甲醇提取物中分离出五种三萜糖苷,通过对其1H、13C和二维核磁共振数据的详细分析以及水解裂解结果得以证实。还分离并鉴定出三种已知的三萜和六种已知的三萜糖苷。对分离出的化合物进行了针对HSC-2细胞和HGF的细胞毒性活性评估。

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