Bustamante C, Keller D, Oster G
Howard Hughes Medical Institute, Department of Physics, University of California, Berkeley, California 94720, USA.
Acc Chem Res. 2001 Jun;34(6):412-20. doi: 10.1021/ar0001719.
Molecular motors convert chemical energy into mechanical force and movement. Operating at energies just above those of the thermal bath, these motors experience large fluctuations, and their physical description must be necessarily stochastic. Here, motor operation is described as a biased diffusion on a potential energy surface defined by the interactions of the motor with its track and its fuel. These ideas are illustrated with a model of the rotary movement of the F(o) motor.
分子马达将化学能转化为机械力和运动。这些马达在略高于热浴能量的条件下运行,会经历大幅涨落,其物理描述必然具有随机性。在此,马达的运行被描述为在由马达与其轨道及燃料之间的相互作用所定义的势能面上的有偏扩散。通过F(o)马达旋转运动的模型对这些观点进行了阐释。