墨西哥奶牛群中的新孢子虫病：胎儿的病变及犬新孢子虫的免疫组织化学检测
Neosporosis in Mexican dairy herds: lesions and immunohistochemical detection of Neospora caninum in fetuses.
作者信息
Morales E, Trigo F J, Ibarra F, Puente E, Santacruz M
机构信息
Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónama de México, 04510, México, D.F.
出版信息
J Comp Pathol. 2001 Jul;125(1):58-63. doi: 10.1053/jcpa.2001.0477.
Of 211 aborted bovine fetuses collected from Mexican dairy herds between January 1996 and March 1999, 73 showed microscopical lesions consistent with neosporosis. Of these 73 fetuses, 58 (79%) showed lymphocytic myocarditis, 39 (53%) showed microgliosis and multifocal necrosis in the brain, 39 (53%) showed lymphocytic hepatitis, and 19 (26%) showed lymphocytic myositis. Immunohistochemical examination of brain, myocardium and liver from 53 of the same 73 fetuses demonstrated Neospora caninum antigens in 41 (77%), of which 19 (46%) gave positive results in one of the three sites, 15 (37%) in two, and seven (17%) in three. The results indicated the presence of neosporosis in a number of the main dairy farming regions of Mexico.
在1996年1月至1999年3月期间从墨西哥奶牛场收集的211例流产牛胎儿中，73例显示出与新孢子虫病相符的微观病变。在这73例胎儿中，58例（79%）表现为淋巴细胞性心肌炎，39例（53%）表现为脑内小胶质细胞增生和多灶性坏死，39例（53%）表现为淋巴细胞性肝炎，19例（26%）表现为淋巴细胞性肌炎。对这73例胎儿中的53例的脑、心肌和肝脏进行免疫组织化学检查，结果显示41例（77%）存在犬新孢子虫抗原，其中19例（46%）在三个部位中的一个呈阳性，15例（37%）在两个部位呈阳性，7例（17%）在三个部位均呈阳性。结果表明墨西哥一些主要奶牛养殖地区存在新孢子虫病。
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