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金盐对炎症反应和炎症细胞功能的作用。

Action of gold salts on the inflammatory response and inflammatory cell function.

作者信息

Vernon-Roberts B

出版信息

J Rheumatol Suppl. 1979;5:120-9.

PMID:114642
Abstract

Information relating to the effect and mechanism of action of gold salts on acute and chronic inflammatory processes has been reviewed. Gold salts are effective in suppressing various aspects of the acute inflammatory process although large gaps exist in the knowledge of the mechanisms involved. Available evidence indicates that gold salts affect many biochemical pathways and that interaction with enzymes plays a major role in their pharmacology. Because they are more difficult to investigate, the action of gold salts on various important aspects of chronic inflammation have not yet received much attention.

摘要

有关金盐对急慢性炎症过程的作用及作用机制的信息已被综述。金盐在抑制急性炎症过程的各个方面是有效的,尽管在涉及的机制方面存在很大的知识空白。现有证据表明,金盐影响许多生化途径,并且与酶的相互作用在其药理学中起主要作用。由于它们更难研究,金盐对慢性炎症各个重要方面的作用尚未受到太多关注。

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Action of gold salts on the inflammatory response and inflammatory cell function.金盐对炎症反应和炎症细胞功能的作用。
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引用本文的文献

1
Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.巴利·弗农-罗伯茨教授,AO,医学博士,理学学士,哲学博士,FRCPath,FRCPA,FAOrthA(荣誉),FRS.SA。
Inflammopharmacology. 2013 Aug;21(4):269-77. doi: 10.1007/s10787-013-0176-6. Epub 2013 Jul 4.
2
Assessment of modified gold surfaced titanium implants on skeletal fixation.改良金面钛种植体在骨骼固定中的评估。
J Biomed Mater Res A. 2013 Jan;101(1):195-202. doi: 10.1002/jbm.a.34307. Epub 2012 Jul 30.
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Effects of dissolucytotic gold ions on recovering brain lesions.
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Randomised controlled trial of extraarticular gold bead implantation for treatment of knee osteoarthritis: a pilot study.关节外植入金珠治疗膝骨关节炎的随机对照试验:一项初步研究
Clin Rheumatol. 2008 Nov;27(11):1363-9. doi: 10.1007/s10067-008-0918-9. Epub 2008 May 24.
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Inhibition of trypsin and papain by sodium aurothiomalate mediated by exchange reactions.通过交换反应,金硫代苹果酸钠对胰蛋白酶和木瓜蛋白酶的抑制作用。
Br J Pharmacol. 1982 Feb;75(2):333-9. doi: 10.1111/j.1476-5381.1982.tb08791.x.
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Improvement in peripheral blood lymphocyte response to concanavalin A and pokeweed mitogen during gold treatment of rheumatoid arthritis.类风湿关节炎金治疗期间外周血淋巴细胞对刀豆球蛋白A和商陆有丝分裂原反应的改善。
Agents Actions. 1980 Dec;10(6):507-8. doi: 10.1007/BF02024152.
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Changes in immune function in patients with rheumatoid arthritis following treatment with sodium aurothiomalate.金硫代苹果酸钠治疗类风湿关节炎患者后免疫功能的变化。
Ann Rheum Dis. 1981 Jun;40(3):254-62. doi: 10.1136/ard.40.3.254.
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Auranofin. A preliminary review of its pharmacological properties and therapeutic use in rheumatoid arthritis.金诺芬。其药理特性及在类风湿性关节炎治疗中的应用的初步综述。
Drugs. 1984 May;27(5):378-424. doi: 10.2165/00003495-198427050-00002.
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