Vernon-Roberts B
J Rheumatol Suppl. 1979;5:120-9.
Information relating to the effect and mechanism of action of gold salts on acute and chronic inflammatory processes has been reviewed. Gold salts are effective in suppressing various aspects of the acute inflammatory process although large gaps exist in the knowledge of the mechanisms involved. Available evidence indicates that gold salts affect many biochemical pathways and that interaction with enzymes plays a major role in their pharmacology. Because they are more difficult to investigate, the action of gold salts on various important aspects of chronic inflammation have not yet received much attention.
有关金盐对急慢性炎症过程的作用及作用机制的信息已被综述。金盐在抑制急性炎症过程的各个方面是有效的,尽管在涉及的机制方面存在很大的知识空白。现有证据表明,金盐影响许多生化途径,并且与酶的相互作用在其药理学中起主要作用。由于它们更难研究,金盐对慢性炎症各个重要方面的作用尚未受到太多关注。