Varni J W, Seid M, Kurtin P S
Center for Child Health Outcomes, Children's Hospital and Health Center, San Diego, California, USA.
Med Care. 2001 Aug;39(8):800-12. doi: 10.1097/00005650-200108000-00006.
The PedsQL (Pediatric Quality of Life Inventory) (Children's Hospital and Health Center, San Diego, California) is a modular instrument for measuring health-related quality of life (HRQOL) in children and adolescents ages 2 to 18. The PedsQL 4.0 Generic Core Scales are multidimensional child self-report and parent proxy-report scales developed as the generic core measure to be integrated with the PedsQL Disease-Specific Modules. The PedsQL 4.0 Generic Core Scales consist of 23 items applicable for healthy school and community populations, as well as pediatric populations with acute and chronic health conditions.
The 4 PedsQL 4.0 Generic Core Scales (Physical, Emotional, Social, School) were administered to 963 children and 1,629 parents (1,677 subjects accrued overall) recruited from pediatric health care settings. Item-level and scale-level measurement properties were computed.
Internal consistency reliability for the Total Scale Score (alpha = 0.88 child, 0.90 parent report), Physical Health Summary Score (alpha = 0.80 child, 0.88 parent), and Psychosocial Health Summary Score (alpha = 0.83 child, 0.86 parent) were acceptable for group comparisons. Validity was demonstrated using the known-groups method, correlations with indicators of morbidity and illness burden, and factor analysis. The PedsQL distinguished between healthy children and pediatric patients with acute or chronic health conditions, was related to indicators of morbidity and illness burden, and displayed a factor-derived solution largely consistent with the a priori conceptually-derived scales.
The results demonstrate the reliability and validity of the PedsQL 4.0 Generic Core Scales. The PedsQL 4.0 Generic Core Scales may be applicable in clinical trials, research, clinical practice, school health settings, and community populations.
儿童生活质量量表（PedsQL）（加利福尼亚州圣地亚哥儿童医院及健康中心）是一种模块化工具，用于测量2至18岁儿童和青少年与健康相关的生活质量（HRQOL）。儿童生活质量量表4.0通用核心量表是多维度的儿童自评和家长代理报告量表，作为通用核心测量工具开发，可与儿童生活质量量表特定疾病模块相结合。儿童生活质量量表4.0通用核心量表由23个项目组成，适用于健康的学校和社区人群以及患有急慢性健康状况的儿科人群。
对从儿科医疗机构招募的963名儿童和1629名家长（共纳入1677名受试者）施测4个儿童生活质量量表4.0通用核心量表（身体、情感、社会、学校）。计算了项目层面和量表层面的测量属性。
总量表得分（儿童α = 0.88，家长报告α = 0.90）、身体健康总结得分（儿童α = 0.80，家长α = 0.88）和心理社会健康总结得分（儿童α = 0.83，家长α = 0.86）的内部一致性信度对于组间比较是可接受的。使用已知群体法、与发病率和疾病负担指标的相关性以及因子分析证明了效度。儿童生活质量量表能够区分健康儿童和患有急慢性健康状况的儿科患者，与发病率和疾病负担指标相关，并且显示出一个因子衍生的解决方案，在很大程度上与先验概念衍生的量表一致。
结果证明了儿童生活质量量表4.0通用核心量表的信度和效度。儿童生活质量量表4.0通用核心量表可能适用于临床试验、研究、临床实践、学校健康环境和社区人群。
