慢性缺氧对大鼠颈动脉体I型细胞数量和细胞核直径的影响。
The effect of chronic hypoxia on the number and nuclear diameter of type I cells in the carotid bodies of rats.
作者信息
Laidler P, Kay J M
出版信息
Am J Pathol. 1975 May;79(2):311-20.
Abstract
We measured the number and nuclear diameter of type I cells in the carotid bodies of 10 normal rats and in 10 rats living in a hypobaric chamber at a pressure of 460 mm Hg for 25 to 96 days. In normal rats, the number of type I rats, the number ranged from 15.92 to 30.77 times 10-3 with a mean of 40.79 times 10-3 which differed significantly from that in the control group. In 5 hypoxic rats the number of type I cells was less than the highest figure in the control group. The mean diameter of the nuclei of type I cells of hypoxic rats (5.5 mu) was greater than that of the controls (5.0 mu). The largest type I nuclei were seen in those rats which had been subjected to hypoxia for the shortest time.
摘要
我们测量了10只正常大鼠以及10只在460毫米汞柱压力的低压舱中生活25至96天的大鼠颈动脉体中I型细胞的数量和细胞核直径。在正常大鼠中，I型细胞数量在15.92×10⁻³至30.77×10⁻³之间，平均为40.79×10⁻³，这与对照组有显著差异。在5只低氧大鼠中，I型细胞数量少于对照组的最高值。低氧大鼠I型细胞核的平均直径（5.5微米）大于对照组（5.0微米）。在低氧时间最短的那些大鼠中可见到最大的I型细胞核。
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