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慢性缺氧对大鼠颈动脉体I型细胞数量和细胞核直径的影响。

The effect of chronic hypoxia on the number and nuclear diameter of type I cells in the carotid bodies of rats.

作者信息

Laidler P, Kay J M

出版信息

Am J Pathol. 1975 May;79(2):311-20.

PMID:1146963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1913023/
Abstract

We measured the number and nuclear diameter of type I cells in the carotid bodies of 10 normal rats and in 10 rats living in a hypobaric chamber at a pressure of 460 mm Hg for 25 to 96 days. In normal rats, the number of type I rats, the number ranged from 15.92 to 30.77 times 10-3 with a mean of 40.79 times 10-3 which differed significantly from that in the control group. In 5 hypoxic rats the number of type I cells was less than the highest figure in the control group. The mean diameter of the nuclei of type I cells of hypoxic rats (5.5 mu) was greater than that of the controls (5.0 mu). The largest type I nuclei were seen in those rats which had been subjected to hypoxia for the shortest time.

摘要

我们测量了10只正常大鼠以及10只在460毫米汞柱压力的低压舱中生活25至96天的大鼠颈动脉体中I型细胞的数量和细胞核直径。在正常大鼠中,I型细胞数量在15.92×10⁻³至30.77×10⁻³之间,平均为40.79×10⁻³,这与对照组有显著差异。在5只低氧大鼠中,I型细胞数量少于对照组的最高值。低氧大鼠I型细胞核的平均直径(5.5微米)大于对照组(5.0微米)。在低氧时间最短的那些大鼠中可见到最大的I型细胞核。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6040/1913023/78aa3ddd271e/amjpathol00462-0133-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6040/1913023/84533d7bbffe/amjpathol00462-0133-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6040/1913023/78aa3ddd271e/amjpathol00462-0133-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6040/1913023/84533d7bbffe/amjpathol00462-0133-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6040/1913023/78aa3ddd271e/amjpathol00462-0133-b.jpg

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The identification of dopamine in the rabbit's carotid body.兔颈动脉体中多巴胺的鉴定。
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[Observations on the glomus caroticum of rats maintained at a simulated altitude of 7500 m].[对处于模拟海拔7500米环境下大鼠颈动脉体的观察]
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