鉴定与新爆发的角结膜炎有关的腺病毒六邻体区域。
Identification of the hexon region of an adenovirus involved in a new outbreak of keratoconjunctivitis.
作者信息
Imai Y, Kameya S, Ohkoshi M, Yamaki K, Sakuragi S
机构信息
Department of Ophthalmology, Akita University School of Medicine, Hondo Akita City, Japan 010-8543.
出版信息
J Clin Microbiol. 2001 Aug;39(8):2975-7. doi: 10.1128/JCM.39.8.2975-2977.2001.
Abstract
We tested 15 adenovirus (Ad)-positive patients involved in a case of nosocomial spread of keratoconjunctivitis. A neutralization test, PCR-restriction fragment length polymorphism analysis, and sequencing of the hypervariable regions of the hexons were performed in order to identify the type of Ad involved. The serotype of the Ad was not identical to any published Ad sequence by either method.
摘要
我们对15例腺病毒（Ad）阳性患者进行了检测，这些患者涉及一起医院内传播的角结膜炎病例。为了确定所涉及的腺病毒类型，进行了中和试验、聚合酶链反应-限制性片段长度多态性分析以及六邻体高变区测序。通过这两种方法，该腺病毒的血清型与任何已发表的腺病毒序列均不相同。
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