头孢唑林与头孢噻吩所致静脉炎的双盲比较。
Double-blind comparison of phlebitis produced by cefazolin versus cephalothin.
作者信息
Shemonsky N K, Carrizosa J C, Kaye D, Levison M E
出版信息
Antimicrob Agents Chemother. 1975 Apr;7(4):481-2. doi: 10.1128/AAC.7.4.481.
Abstract
In a double-blind study with each patient as his own control, 1 g of cefazolin and 2 g of cephalothin were administered intravenously every 6 h to 20 patients in opposite arms for a period of 48 h each. The degree of phlebitis was significantly more severe with cephalothin than with cefazolin (P < 0.05); however, neither the incidence of phlebitis nor the time of onset of phlebitis was significantly different between the two drugs.
摘要
在一项以每位患者自身作为对照的双盲研究中，对20名患者的双臂分别每6小时静脉注射1克头孢唑林和2克头孢噻吩，各持续48小时。头孢噻吩所致静脉炎的严重程度显著高于头孢唑林（P<0.05）；然而，两种药物的静脉炎发生率及静脉炎发作时间并无显著差异。
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J Infect Dis. 1973 Oct;128:Suppl:S341-6. doi: 10.1093/infdis/128.supplement_2.s341.
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Evaluation of cefazolin in the treatment of bacterial endocarditis and bacteremia.头孢唑林治疗细菌性心内膜炎和菌血症的评估。
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Cefazolin in the treatment of bacterial pneumonia.
J Infect Dis. 1973 Oct;128:Suppl:S382-5. doi: 10.1093/infdis/128.supplement_2.s382.
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