Carrizosa J, Levison M E, Kaye D
Antimicrob Agents Chemother. 1973 Feb;3(2):306-7. doi: 10.1128/AAC.3.2.306.
In a double-blind study with each patient as his own control cephapirin and cephalothin were administered to 20 patients in opposite arms for a period of 48 hr each. Neither the incidence of phlebitis nor the degree of phlebitis was significantly different with the two drugs, and there was no difference in the time of onset of pain or phlebitis.
在一项双盲研究中,以每位患者自身作为对照,将头孢匹林和头孢噻吩分别给予20名患者的双侧手臂,各用药48小时。两种药物的静脉炎发生率和静脉炎程度均无显著差异,疼痛或静脉炎的发作时间也无差异。