Carrizosa J, Levison M E, Kaye D
Antimicrob Agents Chemother. 1974 Feb;5(2):192-3. doi: 10.1128/AAC.5.2.192.
In a double-blind study with each patient as his own control, a buffered and an unbuffered cephalothin solution was administered to 13 patients in opposite arms for a period of 48 h each. Neither the incidence of phlebitis nor the degree of phlebitis was different with the two diluents, and there was no difference in the time of onset of phlebitis.
在一项以每位患者自身作为对照的双盲研究中，给13名患者的双臂分别注射缓冲型头孢噻吩溶液和非缓冲型头孢噻吩溶液，每次注射持续48小时。两种稀释剂引发静脉炎的发生率和严重程度均无差异，静脉炎的发作时间也无差异。
