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益生菌良好的黏附特性:会是菌血症的一个潜在风险吗?

Good adhesion properties of probiotics: a potential risk for bacteremia?

作者信息

Apostolou E, Kirjavainen P V, Saxelin M, Rautelin H, Valtonen V, Salminen S J, Ouwehand A C

机构信息

Department of Biochemistry and Food Chemistry, University of Turku, Finland.

出版信息

FEMS Immunol Med Microbiol. 2001 Jul;31(1):35-9. doi: 10.1111/j.1574-695X.2001.tb01583.x.

DOI:10.1111/j.1574-695X.2001.tb01583.x
PMID:11476979
Abstract

The ability to adhere to human intestinal mucus was tested for lactic acid bacteria of clinical blood culture, human fecal and dairy origin. The blood culture isolates were found to adhere better than the dairy strains. Of the Lactobacillus rhamnosus strains (nine clinical, 10 fecal and three dairy), blood culture isolates adhered better than the fecal strains. Although these results indicate a trend for blood culture isolates to bind to intestinal mucus in higher numbers than strains of dairy and human fecal origin, other factors are also likely to be involved in the etiology of lactobacillemia since some of the clinical Lactobacillus isolates exhibited a relatively low level of adhesion.

摘要

对源自临床血培养、人类粪便和乳制品的乳酸菌进行了黏附人肠黏液能力的测试。结果发现,血培养分离株的黏附能力优于乳制品菌株。在鼠李糖乳杆菌菌株(9株临床分离株、10株粪便分离株和3株乳制品分离株)中,血培养分离株的黏附能力优于粪便分离株。尽管这些结果表明血培养分离株比乳制品和人类粪便来源的菌株更易与肠黏液结合,但由于一些临床乳酸杆菌分离株的黏附水平相对较低,其他因素可能也参与了乳酸菌血症的病因。

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