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菌血症相关乳酸杆菌的体外黏附及血小板聚集特性

In vitro adhesion and platelet aggregation properties of bacteremia-associated lactobacilli.

作者信息

Kirjavainen P V, Tuomola E M, Crittenden R G, Ouwehand A C, Harty D W, Morris L F, Rautelin H, Playne M J, Donohue D C, Salminen S J

机构信息

Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland.

出版信息

Infect Immun. 1999 May;67(5):2653-5. doi: 10.1128/IAI.67.5.2653-2655.1999.

Abstract

Eight bacteremia-associated Lactobacillus strains were evaluated in vitro for the ability to adhere to human intestinal mucosa and to aggregate platelets. Adherence varied significantly among the strains, and platelet aggregation was induced by three strains. In conclusion, strong binding ability does not appear to be a prerequisite for the involvement of lactobacilli in bacteremia or to their ability to aggregate platelets.

摘要

对八株与菌血症相关的乳酸杆菌菌株进行了体外评估,以检测它们黏附于人类肠黏膜和凝集血小板的能力。各菌株间的黏附能力差异显著,有三株菌株可诱导血小板凝集。总之,对于乳酸杆菌参与菌血症或其凝集血小板的能力而言,强大的结合能力似乎并非必要条件。

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