Rönnemaa T, Juva K, Kulonen E
Atherosclerosis. 1975 May-Jun;21(3):315-24. doi: 10.1016/0021-9150(75)90045-3.
The effect of hyperlipidemic rat serum and its fractions on the synthetic functions of embryonic fibroblasts was studied. Moderately hypercholesterolemic sera (100-140 mg/100 ml) stimulated the synthesis of collagen, but not the synthesis of non-collagenous proteins nor the incorporation of glucosamine or cytidine. The stimulating principle was nondialyzable. It was not associated with the isolated total lipoproteins but was found in the infranatant fraction of sera centrifuged at a density of 1.220.
研究了高脂血症大鼠血清及其组分对胚胎成纤维细胞合成功能的影响。中度高胆固醇血症血清（100 - 140毫克/100毫升）刺激胶原蛋白的合成，但不刺激非胶原蛋白的合成，也不刺激氨基葡萄糖或胞苷的掺入。刺激原理是不可透析的。它与分离出的总脂蛋白无关，但存在于密度为1.220离心的血清的下层组分中。
