Gupta N M, Gupta R, Rao M S, Gupta V
Department of Surgery, Postgraduate Institute of Medical Education and Research, 160012, Chandigarh, India.
Am J Surg. 2001 Jun;181(6):534-9. doi: 10.1016/s0002-9610(01)00616-x.
The anastomotic leak and stricture formation after esophagectomy and cervical esophagogastric anastomosis deny patients with esophageal carcinoma the benefits of surgery. The present study was designed to ascertain whether a wide cross-sectional area at the site of anastomosis leads to lesser anastomotic complications.
One hundred patients with resectable carcinoma of the esophagus were randomly distributed into two groups of 50 each. All patients underwent one-stage transhiatal esophagectomy. In group A, 3 x 2 cm gastric crescent was excised from the anterior wall of the gastric tube before constructing the cervical esophagogastric anastomosis. No such intervention was done in group B, which acted as control. All patients were followed up for at least 3 months for detection of anastomotic complications.
The incidence of anastomotic leak in the study group was significantly less in comparison with the control group (4.3% versus 20.8%; P = 0.03). Similarly, anastomotic stricture formation was significantly lower in the study group (8.5% versus 29.2%; P = 0.02).
A wide cross-sectional area achieved at the anastomotic site by removal of gastric crescent resulted in significantly lower anastomotic complications.
食管癌切除术后行颈部食管胃吻合术出现的吻合口漏和狭窄形成,使食管癌患者无法从手术中获益。本研究旨在确定吻合口处较大的横截面积是否会导致较少的吻合口并发症。
100例可切除食管癌患者随机分为两组,每组50例。所有患者均接受一期经胸食管切除术。A组在构建颈部食管胃吻合术前,从胃管前壁切除3×2cm的胃月牙形组织。B组作为对照组,未进行此类干预。所有患者均随访至少3个月以检测吻合口并发症。
研究组吻合口漏的发生率显著低于对照组(4.3%对20.8%;P = 0.03)。同样,研究组吻合口狭窄形成的发生率也显著更低(8.5%对29.2%;P = 0.02)。
通过切除胃月牙形组织在吻合口处获得较大的横截面积,可显著降低吻合口并发症的发生率。