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孤立性直肠溃疡综合征:13例患者的系列研究,平均随访4.5年。

Solitary rectal ulcer syndrome: a series of 13 patients operated with a mean follow-up of 4.5 years.

作者信息

Marchal F, Bresler L, Brunaud L, Adler S C, Sebbag H, Tortuyaux J M, Boissel P

机构信息

Department of Gastro-Intestinal Surgery C, Brabois Hospital, Vandoeuvre-les-Nancy, France.

出版信息

Int J Colorectal Dis. 2001 Aug;16(4):228-33. doi: 10.1007/s003840100303.

DOI:10.1007/s003840100303
PMID:11515682
Abstract

Solitary rectal ulcer syndrome (SRUS) is an infrequent pathology often associated with pelvic floor disorders. The aim of this retrospective study was to review the long-term results of a surgical series of SRUS. Between 1988 and 1998, 13 patients were operated on for SRUS. Seven patients had associated internal rectal prolapse (58%), two had associated total rectal prolapse (15%), and two had associated mucosal prolapse (15%). We performed simple resection of the SRUS in one case (8%), a stoma as primary operation in one (8%), three rectopexies according to Orr-Loygue (23%), and eight Delorme's operations as modified by Berman (62%). Mean follow-up was 57 months (range 15-112). Simple resection of the solitary rectal ulcer syndrome did not improve symptoms. Colostomy permitted relief of symptoms and healing of the SRUS. Two of the three rectopexies achieved good results, and the third patient relapsed at the 6th postoperative month. A secondary modified Delorme's operation permitted relief of symptoms and healing of the SRUS. Five of the eight patients (62.5%) who received modified Delorme's operations had improved at a follow-up of 46 months. We conclude that, considering the high failure rate after surgery, operations should be performed only in patients with total rectal prolapse or intractable symptoms not amenable to behavioral therapy. Delorme's operation and abdominal rectopexy help in about 60% of cases.

摘要

孤立性直肠溃疡综合征(SRUS)是一种罕见的病理状况,常与盆底功能障碍相关。本回顾性研究的目的是回顾一系列SRUS手术的长期结果。1988年至1998年间,13例患者接受了SRUS手术。7例患者合并直肠内脱垂(58%),2例合并完全直肠脱垂(15%),2例合并黏膜脱垂(15%)。1例患者(8%)行SRUS单纯切除术,1例(8%)以造口术作为一期手术,3例按奥尔-洛伊格法行直肠固定术(23%),8例按伯曼改良法行德洛姆手术(62%)。平均随访时间为57个月(范围15 - 112个月)。孤立性直肠溃疡综合征单纯切除术未能改善症状。结肠造口术可缓解症状并使SRUS愈合。3例直肠固定术中2例取得良好效果,第3例患者术后6个月复发。二次改良德洛姆手术可缓解症状并使SRUS愈合。8例接受改良德洛姆手术的患者中,5例(62.5%)在46个月的随访时症状改善。我们得出结论,鉴于手术后的高失败率,手术应仅针对完全直肠脱垂或经行为治疗无效的顽固性症状患者进行。德洛姆手术和经腹直肠固定术在约60%的病例中有效。

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A systematic review and meta-analysis of the efficacy of medical treatments for the management of solitary rectal ulcer syndrome.系统评价和荟萃分析医疗治疗孤立性直肠溃疡综合征的疗效。
Saudi J Gastroenterol. 2020 Jan-Feb;26(1):4-12. doi: 10.4103/sjg.SJG_213_19.
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Middle East J Dig Dis. 2019 Jul;11(3):129-134. doi: 10.15171/mejdd.2019.138. Epub 2019 Jun 28.
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[Pelvic floor and anal incontinence. Conservative therapy].[盆底与肛门失禁。保守治疗]
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