Sitzler P J, Kamm M A, Nicholls R J, McKee R F
Department of Surgery, St Mark's Hospital, Harrow, UK.
Br J Surg. 1998 Sep;85(9):1246-50. doi: 10.1046/j.1365-2168.1998.00854.x.
When severe symptoms of solitary rectal ulcer syndrome persist despite medical management, surgery may be necessary.
A retrospective review was carried out of 81 patients undergoing surgery for solitary rectal ulcer syndrome in the 10-year period from 1984 to 1993 to determine the long-term outcome at a minimum follow-up of 12 months. Of the 81 patients, 15 were excluded from further analysis (11 were followed up for less than 12 months, two died and two were lost to follow-up). Sixty-six patients were studied (median age 38 (range 15-77) years; 53 female). Of these, 49 underwent rectopexy, nine Delorme's operation, two anterior resection and four creation of a stoma as the initial operation.
At a median follow-up of 90 (range 12-177) months, the rectopexy had failed in 22 of 49 patients; 19 of these patients underwent further surgery, including rectal resection with coloanal anastomosis (four with three failures), colostomy (11) and other procedures (four). Ultimately, 14 required a stoma. Constipation was the indication for a stoma in nine of the 11 patients who had colostomy as the first procedure after failure of rectopexy. Nine patients had Delorme's operation as the first procedure. At median follow-up of 38 (range 19-107) months, there were four failures. Two of these ultimately required a stoma. Of the seven patients who underwent anterior resection as the initial or subsequent procedure, a stoma was finally necessary in four. Anterior resection used as a salvage procedure was not successful. The overall stoma rate was 30 per cent (20 patients). Of 11 symptoms assessed before operation only incontinence and incomplete evacuation were related to a poor outcome following surgery.
Antiprolapse operations result in a satisfactory long-term outcome in about 55-60 per cent of patients having surgery for solitary rectal ulcer syndrome. Results of anterior resection are disappointing.
尽管采取了药物治疗,但如果孤立性直肠溃疡综合征的严重症状持续存在,则可能需要进行手术。
对1984年至1993年这10年间接受孤立性直肠溃疡综合征手术的81例患者进行回顾性研究,以确定至少随访12个月的长期结果。81例患者中,15例被排除在进一步分析之外(11例随访时间不足12个月,2例死亡,2例失访)。对66例患者进行了研究(中位年龄38岁(范围15 - 77岁);53例为女性)。其中,49例行直肠固定术,9例行德洛姆手术,2例行前切除术,4例行造口术作为初始手术。
中位随访90个月(范围12 - 177个月)时,49例行直肠固定术的患者中有22例失败;其中19例患者接受了进一步手术,包括直肠切除结肠肛管吻合术(4例,其中3例失败)、结肠造口术(11例)和其他手术(4例)。最终,14例需要造口。在直肠固定术失败后首次接受结肠造口术的11例患者中,9例因便秘而行造口术。9例患者首次接受德洛姆手术。中位随访38个月(范围19 - 107个月)时,有4例失败。其中2例最终需要造口。在7例接受前切除术作为初始或后续手术的患者中,4例最终需要造口。用作挽救性手术的前切除术未成功。总体造口率为30%(20例患者)。在术前评估的11种症状中,只有失禁和排便不净与术后不良结局相关。
对于因孤立性直肠溃疡综合征接受手术的患者,抗脱垂手术在约55% - 60%的患者中可产生令人满意的长期结果。前切除术的结果令人失望。