De Giglio E, Guascito M R, Sabbatin L, Zambonin G
Dipartimento di Chimica, Università degli Studi di Bari, Italy.
Biomaterials. 2001 Oct;22(19):2609-16. doi: 10.1016/s0142-9612(00)00449-x.
Titanium and its alloys are widely used in load-bearing implants as a result of their excellent mechanical properties and corrosion resistance. In order to improve their performances with respect to osseointegration, the use of bioactive coatings has been suggested. Polypyrrole (PPy) has been chosen as coating polymer because of its ability to be electrochemically grown directly onto metallic substrates, of any shape and dimension, leading to remarkably adherent overlayers. This polymer, in addition to protecting the metal implant against corrosion, could be surface modified with biologically active molecules able to stimulate positive interactions with bone tissue. In this work, PPy electrosynthesis on both titanium and Ti-Al-V substrates has been investigated. The chemical composition and the morphology of the polymeric films, deposited under different conditions, were evaluated by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM), respectively.
钛及其合金因其优异的机械性能和耐腐蚀性而被广泛应用于承重植入物。为了改善它们在骨整合方面的性能，有人建议使用生物活性涂层。聚吡咯（PPy）被选作涂层聚合物，因为它能够通过电化学方法直接生长在任何形状和尺寸的金属基底上，从而形成附着力很强的覆盖层。这种聚合物除了能保护金属植入物免受腐蚀外，还可以用能够刺激与骨组织产生积极相互作用的生物活性分子进行表面改性。在这项工作中，研究了在钛和Ti-Al-V基底上进行聚吡咯的电合成。分别通过X射线光电子能谱（XPS）和扫描电子显微镜（SEM）对在不同条件下沉积的聚合物薄膜的化学成分和形态进行了评估。
