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艾滋病医疗补助受益人群中蛋白酶抑制剂和非核苷类逆转录酶抑制剂的使用情况。

Use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors among Medicaid beneficiaries with AIDS.

作者信息

Sambamoorthi U, Moynihan P J, McSpiritt E, Crystal S

机构信息

Institute for Health, Health Care Policy, and Aging Research, Rutgers University, New Brunswick, NJ 08901, USA.

出版信息

Am J Public Health. 2001 Sep;91(9):1474-81. doi: 10.2105/ajph.91.9.1474.

Abstract

OBJECTIVES

This study compared the use of new antiretroviral treatments across sociodemographic subgroups during the 3 years after the introduction of these treatments and examined diffusion of the therapies over time.

METHODS

Merged surveillance and claims data were used to examine use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors (PI/NNRTIs) among New Jersey Medicaid beneficiaries with AIDS.

RESULTS

In 1996, there were sharp disparities in use of PI/NNRTI therapy among racial minorities and injection drug users, even after control for other patient characteristics. These gaps had decreased by 1998. Higher PI/NNRTI treatment rates were also observed among beneficiaries enrolled in a statewide HIV/AIDS-specific home- and community-based Medicaid waiver program.

CONCLUSIONS

Even within a population of individuals similar in regard to health coverage, there were substantial sociodemographic differences in use of PI/NNRTIs during the early years after their introduction. These differences narrowed as new treatments became standard. Participation in a case-managed Medicaid waiver program seems to be associated with a more appropriate pattern of use. These results suggest a need to address nonfinancial barriers to care.

摘要

目的

本研究比较了新抗逆转录病毒治疗在引入后的3年里在不同社会人口学亚组中的使用情况,并考察了这些治疗方法随时间的传播情况。

方法

利用合并的监测和索赔数据,研究新泽西州艾滋病医疗补助受益人群中蛋白酶抑制剂和非核苷类逆转录酶抑制剂(PI/NNRTIs)的使用情况。

结果

1996年,即使在控制了其他患者特征之后,少数族裔和注射吸毒者在PI/NNRTI治疗的使用上仍存在显著差异。到1998年,这些差距有所缩小。在参加全州范围内针对艾滋病毒/艾滋病的特定家庭和社区医疗补助豁免计划的受益人中,PI/NNRTI的治疗率也更高。

结论

即使在健康保险情况相似的人群中,PI/NNRTIs在引入后的最初几年里,其使用在社会人口学方面也存在很大差异。随着新治疗方法成为标准治疗,这些差异逐渐缩小。参与病例管理的医疗补助豁免计划似乎与更合适的使用模式相关。这些结果表明需要消除医疗护理的非财务障碍。

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