Richards C A, Milla P J, Andrews P L, Spitz L
Department of Surgery, Institute of Child Health, London, England.
J Pediatr Surg. 2001 Sep;36(9):1401-4. doi: 10.1053/jpsu.2001.26384.
BACKGROUND/PURPOSE: In neurologically impaired children, retching and recurrent vomiting are common after Nissen fundoplication. The aim of this study was to identify whether there are preoperative factors that predict their occurrence.
Twenty neurologically impaired children (8 boys, 12 girls; age range, 3 months to 8 years) were studied prospectively by taking a detailed history of behaviors and symptoms associated with feeding before and after Nissen fundoplication for gastroesophageal reflux.
Preoperatively, children could be classified into 2 groups. Children in group A had symptoms suggestive of only gastroesophageal reflux (effortless "vomiting" or regurgitation), whereas children in group B exhibited one or more features associated with activation of the emetic reflex (pallor, sweating, retching, forceful vomiting). Postoperatively 0 of 8 in group A retched compared with 8 of 12 in group B (P <.005, Fishers Exact test).
Children at high risk of retching, and ultimately vomiting, after antireflux surgery may be identified clinically preoperatively. They have symptoms that are specifically caused by activation of the emetic reflex rather than to gastroesophageal reflux. In these cases, antireflux surgery could be considered inappropriate and hence be avoided.
背景/目的:在神经功能受损的儿童中,nissen胃底折叠术后干呕和反复呕吐很常见。本研究的目的是确定是否存在术前因素可预测其发生。
对20名神经功能受损儿童(8名男孩,12名女孩;年龄范围3个月至8岁)进行前瞻性研究,详细记录nissen胃底折叠术治疗胃食管反流前后与喂养相关的行为和症状。
术前,儿童可分为两组。A组儿童仅有胃食管反流症状(无费力的“呕吐”或反流),而B组儿童表现出一种或多种与催吐反射激活相关的特征(面色苍白、出汗、干呕、强力呕吐)。术后,A组8名儿童中0名干呕,而B组12名儿童中有8名干呕(P<.005,Fisher精确检验)。
抗反流手术后有干呕及最终呕吐高风险的儿童在术前可通过临床检查识别。他们的症状是由催吐反射激活而非胃食管反流引起的。在这些情况下,抗反流手术可能被认为不合适,因此应避免。