Hatziioannou T, Goff S P
Department of Biochemistry and Molecular Biophysics and Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
J Virol. 2001 Oct;75(19):9526-31. doi: 10.1128/JVI.75.19.9526-9531.2001.
A direct comparison demonstrates that Rous sarcoma virus is capable of infecting aphidicolin-arrested cells 10-fold more efficiently than murine leukemia virus but less efficiently than human immunodeficiency virus. The efficiency of infection of nondividing cells by the three viruses correlates with the respective ability of each viral DNA to enter the nucleus.
直接比较表明,劳氏肉瘤病毒感染经阿非科林阻滞的细胞的效率比鼠白血病病毒高10倍,但比人类免疫缺陷病毒低。这三种病毒对非分裂细胞的感染效率与每种病毒DNA进入细胞核的相应能力相关。