Hertz J, Cain W S, Bartoshuk L M, Dolan T F
Physiol Behav. 1975 Jan;14(1):89-94. doi: 10.1016/0031-9384(75)90147-x.
Psychophysical experiments measured both olfactory sensitivity to 1-butanol and sodium chloride and taste sensitivity to sodium chloride in normal children and in children with cystic fibrosis. The sensitivity of the children with cystic fibrosis fell within the normal range. These results stand in contrast to those of Henkin and Powell, who found children with cystic fibrosis to be hypersensitive to both olfactory and taste stimuli. Apparent hypersensitivity to taste stimuli could have resulted from the adapting effects of the relatively high level of sodium in the saliva of children with cystic fibrosis. If the contaminating effects of saliva are removed, children with cystic fibrosis yield, on the average, a taste threshold identical to that of normal children. There appears to be no simple explanation for why Henkin and Powell found hypersensitivity to odorants. The present results indicate that, in fact, children with cystic fibrosis display a slight hyposensitivity to odorants.
心理物理学实验测量了正常儿童和患有囊性纤维化的儿童对1 - 丁醇和氯化钠的嗅觉敏感性以及对氯化钠的味觉敏感性。患有囊性纤维化的儿童的敏感性落在正常范围内。这些结果与亨金和鲍威尔的结果形成对比，他们发现患有囊性纤维化的儿童对嗅觉和味觉刺激都过敏。对味觉刺激的明显过敏可能是由于囊性纤维化儿童唾液中相对较高水平的钠的适应作用。如果去除唾液的污染影响，患有囊性纤维化的儿童平均产生的味觉阈值与正常儿童相同。对于为什么亨金和鲍威尔发现对气味剂过敏，似乎没有简单的解释。目前的结果表明，事实上，患有囊性纤维化的儿童对气味剂表现出轻微的低敏感性。
