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大鼠对抛物线飞行的心血管适应性:一项无线电遥测可行性研究。

Cardiovascular adaptations to parabolic flight in rats: a radio-telemetry feasibility study.

作者信息

Somody L, Fagette S, Frutoso J, Gharib C, Blanquie J P, Gharib T, Thierion D, Gauquelin G

机构信息

Laboratoire de Physiologie de l'Environnement, Faculte de Medecine, Lyon, France.

出版信息

J Gravit Physiol. 1997 Jul;4(2):P43-4.

PMID:11540693
Abstract

This experiment was a feasibility study which consisted in investigating arterial blood pressure and heart rate to transient and repeated exposure to microgravity in eight unrestrained rats previously implanted with radio-telemetry transmitter. The aim was to perform such recordings throughout all the phases of a parabola during parabolic flights. This study revealed that it was possible to collect the radio-signal without any interference with electronic or magnetic environment. We observed in microgravity a significant reduction in heart rate (6%) and a significant increase in arterial blood pressure (7%). In conclusion, such a study seems to be feasible during longer exposure to microgravity (space flight) in order to study the cardiovascular adaptation in rat.

摘要

本实验是一项可行性研究,包括对八只预先植入无线电遥测发射器的无束缚大鼠进行短暂和反复暴露于微重力环境下的动脉血压和心率研究。目的是在抛物线飞行的整个抛物线阶段进行此类记录。该研究表明,可以在不干扰电子或磁环境的情况下收集无线电信号。我们观察到在微重力环境下心率显著降低(6%),动脉血压显著升高(7%)。总之,为了研究大鼠的心血管适应性,这样的研究在更长时间暴露于微重力环境(太空飞行)期间似乎是可行的。

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J Gravit Physiol. 1997 Jul;4(2):P43-4.
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