Báthori E, Soltész L
Strahlentherapie. 1975 May;149(5):513-9.
After application of solf X-rays with 100, 500 and 1000 R, the activity change of the acid and alcaline phosphatase in the skin of mice has been studied. The studies happened immediatly after the irradiation and at the 1st, 2nd, 4th, 8th and 16th day. The measurment of the enzyme activity washable out of the skin and remianing in the skin after the washing and the total activity of the skin have been taken up. With the acid phosphatase it would be determined that the quantity washable out of the skin is unusually low; the acitity values of the wash solution increase at the 2nd day after the irradiation in dependence on the applicated dose;at the moment 0 after an irradiation with 1000 R, a significative activity increase in the wash solution appears; the homogenate activity at the 2nd day only gets a significative activity increase after the irradiation with 500 R. The alcaline phosphatase was measurable in the wash solution at no moment of the measurement. However, the alcaline phosphatase has been decreased in the homogenate with few exceptions.
在用100、500和1000伦琴的软X射线照射后,研究了小鼠皮肤中酸性和碱性磷酸酶的活性变化。研究在照射后立即进行,并在第1、2、4、8和16天进行。测定了可从皮肤中洗脱出来的酶活性、洗脱后留在皮肤中的酶活性以及皮肤的总活性。对于酸性磷酸酶,发现可从皮肤中洗脱出来的量异常低;洗脱液的活性值在照射后第2天根据照射剂量而增加;在用1000伦琴照射后0时刻,洗脱液中出现显著的活性增加;仅在用500伦琴照射后,第2天匀浆活性才有显著的活性增加。在测量的任何时刻,洗脱液中均未检测到碱性磷酸酶。然而,除少数例外,匀浆中的碱性磷酸酶活性降低。