Olivo A, Arfelli F, Cantatore G, Longo R, Menk R H, Pani S, Prest M, Poropat P, Rigon L, Tromba G, Vallazza E, Castelli E
Dipartimento di Fisica, Università di Trieste e INFN, Sezione di Trieste, Italy.
Med Phys. 2001 Aug;28(8):1610-9. doi: 10.1118/1.1388219.
Recently, new imaging modalities based on the detection of weak phase perturbations effects, among which are phase contrast and diffraction imaging, have been developed by several researchers. Due to their high sensitivity to weakly absorbing details, these techniques seem to be very promising for applications in the medical field. On the other hand, digital radiology is undergoing a wide diffusion, and its benefits are presently very well understood. Up to now, however, the strong pixel size constraints associated with phase contrast pattern detection limited the possibility of exploiting the advantages of phase contrast in digital radiology applications. In this paper, an innovative setup capable of removing the pixel size constraints, and thus opening the way to low dose digital phase contrast imaging, is described. Furthermore, we introduce an imaging technique based on the detection of radiation scattered at small angles: the information extracted from the sample is increased at no dose expense. We believe that several radiological fields, mammography being the first important example, may benefit from the herein described innovative imaging techniques.
最近，几位研究人员开发了基于检测微弱相位扰动效应的新型成像模态，其中包括相衬成像和衍射成像。由于它们对微弱吸收细节具有高灵敏度，这些技术在医学领域的应用似乎非常有前景。另一方面，数字放射学正在广泛普及，其优势目前已得到很好的理解。然而，到目前为止，与相衬图案检测相关的强烈像素尺寸限制了在数字放射学应用中利用相衬优势的可能性。本文描述了一种创新装置，它能够消除像素尺寸限制，从而为低剂量数字相衬成像开辟道路。此外，我们引入了一种基于检测小角度散射辐射的成像技术：在不增加剂量的情况下增加了从样品中提取的信息。我们相信，几个放射学领域，乳腺摄影是第一个重要例子，可能会从本文所述的创新成像技术中受益。
