Laupland K B, Davies H D
Department of Microbiology and Infectious Diseases, University of Calgary, Alta.
Clin Invest Med. 2001 Aug;24(4):171-8.
The epidemiology, outcome and management of olecranon septic bursitis (OSB) have not been described in a large cohort of ambulatory patients.
A retrospective study of all 118 cases of OSB presenting over 21 months to all regional Home Parenteral Therapy Program clinics in Calgary (referral base approximately 1 million).
The minimum population annual incidence was 10/100,000. The mean (and standard deviation) age was 44 (13) years, and males predominated (88%). One-third of patients had at least one comorbid illness, with preceding injury in 53% of cases. The most common symptoms were pain (87%), redness (77%) and fever or chills (45%). Common signs included erythema (92%), swelling (85%), edema (75%), tenderness (59%), fluctuance (50%), heat (36%) and reduced range of motion (27%). Fever (body temperature of > or =37.8 degrees C) occurred in 20%. Staphylococcus aureus was identified in 88% of culture-proven cases of OBS. The most common antibiotic regimen was sequential intravenous administration of cefazolin (for a median of 4 d) followed by clindamycin orally (for a median of 8 d). Sixty (51%) patients required a drainage procedure and only 1 patient required admission to hospital.
OSB is more common than reported and can be treated successfully in ambulatory settings with sequential intravenous therapy followed by oral therapy and drainage in selected cases.
尺骨鹰嘴化脓性滑囊炎(OSB)的流行病学、转归及治疗在大量门诊患者中尚未见报道。
对卡尔加里所有地区家庭肠外治疗项目诊所21个月内收治的118例OSB患者进行回顾性研究(转诊基数约100万)。
最低人群年发病率为10/100,000。平均(及标准差)年龄为44(13)岁,男性占主导(88%)。三分之一的患者至少有一种合并症,53%的病例有先前损伤史。最常见的症状为疼痛(87%)、发红(77%)及发热或寒战(45%)。常见体征包括红斑(92%)、肿胀(85%)、水肿(75%)、压痛(59%)、波动感(50%)、发热(36%)及活动范围减小(27%)。20%的患者出现发热(体温≥37.8℃)。在88%的经培养证实的OBS病例中鉴定出金黄色葡萄球菌。最常用的抗生素治疗方案是先静脉序贯给予头孢唑林(中位时间4天),随后口服克林霉素(中位时间8天)。60例(51%)患者需要进行引流手术,仅1例患者需要住院治疗。
OSB比报道的更为常见,在门诊环境中采用静脉序贯治疗,随后口服治疗,并在特定病例中进行引流,可成功治疗。