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孕期母亲异食癖行为导致的新生儿铅中毒

Neonatal lead poisoning from maternal pica behavior during pregnancy.

作者信息

Hamilton S, Rothenberg S J, Khan F A, Manalo M, Norris K C

机构信息

Charles Drew University of Medicine and Science and UCLA School of Medicine, Los Angeles, California, USA.

出版信息

J Natl Med Assoc. 2001 Sep;93(9):317-9.

Abstract

Lead toxicity has gained increasing attention in the public media because of its ubiquitous distribution in the environment and the potentially serious medical complications that it can induce, particularly in children. We present a case of an asymptomatic Hispanic woman who exhibited a unique form of pica during her pregnancy. By serendipity, she agreed to enroll into a lead screening study at our medical center when she presented to deliver her child. Her blood lead level was 119.4 microg/dL at delivery, and simultaneous measurement of the neonate's cord blood lead level was 113.6 microg/dL. The infant underwent an exchange transfusion, and the mother was treated with oral 2,3-dimercaptosuccinic acid. Both demonstrated dramatic biochemical improvement.

摘要

由于铅在环境中广泛存在,且可能引发潜在的严重医学并发症,尤其是对儿童,铅中毒在公共媒体上越来越受到关注。我们报告一例无症状的西班牙裔女性病例,她在怀孕期间表现出一种独特的异食癖形式。机缘巧合的是,她在前来我院分娩时同意参加我院的一项铅筛查研究。分娩时她的血铅水平为119.4微克/分升,同时检测的新生儿脐血铅水平为113.6微克/分升。该婴儿接受了换血治疗,母亲接受了口服2,3-二巯基丁二酸治疗。两者均表现出显著的生化指标改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1306/2593967/5b9a107d4dc9/jnma00337-0020-a.jpg

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