Benecke J E
Laryngoscope. 2001 Sep;111(9):1525-7. doi: 10.1097/00005537-200109000-00007.
OBJECTIVE/HYPOTHESIS: The purpose of this work is to evaluate the performance of an acellular dermal allograft (AlloDerm; LifeCell Corp., The Woodlands, TX) in tympanic membrane (TM) grafting.
A retrospective review of 20 consecutive tympanoplasty surgeries using temporalis fascia and 20 consecutive procedures using AlloDerm.
The charts of 20 consecutive adults who underwent tympanoplasty surgery were reviewed to evaluate graft take and hearing results. Similarly, 20 consecutive patients who had TM grafting with AlloDerm were reviewed. Pre- and postoperative air-bone gaps (ABG) at 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz were compared.
There were no graft failures in either the temporalis fascia group or the AlloDerm group. No statistically significant difference was noted in hearing results when comparing the residual conductive loss in both postoperative groups.
AlloDerm is a suitable material for TM grafting. This product is especially valuable in revision surgery in which the availability of appropriate autologous grafting material is limited.
目的/假设：本研究旨在评估脱细胞异体真皮基质（AlloDerm；LifeCell公司，美国得克萨斯州伍德兰兹）在鼓膜（TM）移植中的性能。
对连续20例使用颞肌筋膜的鼓室成形术和连续20例使用AlloDerm的手术进行回顾性研究。
回顾连续20例接受鼓室成形术的成年患者的病历，以评估移植物的存活情况和听力结果。同样，回顾连续20例接受AlloDerm鼓膜移植的患者。比较术前和术后500Hz、1000Hz、2000Hz和4000Hz的气骨导间距（ABG）。
颞肌筋膜组和AlloDerm组均未出现移植物失败。比较两组术后残留传导性听力损失时，听力结果无统计学显著差异。
AlloDerm是一种适合鼓膜移植的材料。该产品在合适的自体移植材料有限的翻修手术中尤其有价值。
