Willumsen J F, Newell M L, Filteau S M, Coutsoudis A, Dwarika S, York D, Tomkins A M, Coovadia H M
Centre for International Child Health, London, UK.
AIDS. 2001 Sep 28;15(14):1896-8. doi: 10.1097/00002030-200109280-00026.
The mechanism and risk factors associated with mother-to-child transmission of HIV-1 through breastfeeding remain unclear; breastmilk viral load may be an important determinant of transmission. Analysis of breastmilk cell-free viral load in samples taken from each breast at 1, 6 and 14 weeks postpartum showed that HIV-1 is shed intermittently and load may differ considerably between breasts of an individual woman at any given time. Breastmilk HIV-1 load was undetectable in approximately one-third of samples.
人类免疫缺陷病毒1型(HIV-1)通过母乳喂养发生母婴传播的机制和风险因素仍不清楚;母乳病毒载量可能是传播的一个重要决定因素。对产后1周、6周和14周从每个乳房采集的母乳无细胞病毒载量进行分析显示,HIV-1是间歇性排出的,并且在任何给定时间,个体女性两侧乳房的病毒载量可能有很大差异。在大约三分之一的样本中检测不到母乳中的HIV-1载量。