Giladi M, Metzkor-Cotter E, Martin D A, Siegman-Igra Y, Korczyn A D, Rosso R, Berger S A, Campbell G L, Lanciotti R S
Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel.
Emerg Infect Dis. 2001 Jul-Aug;7(4):659-61. doi: 10.3201/eid0704.010410.
We describe two cases of West Nile (WN) encephalitis in a married couple in Tel Aviv, Israel, in 1999. Reverse transcription-polymerase chain reaction performed on a brain specimen from the husband detected a WN viral strain nearly identical to avian strains recovered in Israel in 1998 (99.9% genomic sequence homology) and in New York in 1999 (99.8%). This result supports the hypothesis that the 1999 WN virus epidemic in the United States originated from the introduction of a strain that had been circulating in Israel.
1999年,我们在以色列特拉维夫的一对已婚夫妇中发现了两例西尼罗河(WN)脑炎病例。对丈夫的脑标本进行逆转录聚合酶链反应检测,发现一种WN病毒株与1998年在以色列分离出的禽类病毒株几乎相同(基因组序列同源性为99.9%),也与1999年在纽约分离出的病毒株相似(99.8%)。这一结果支持了以下假设:1999年美国的WN病毒疫情源于引入了一种此前在以色列传播的病毒株。