Ichimi K, Suzuki T, Yamasaki M
Tohoku National Fisheries Research Institute, 3-27-5 Shinhama, Shiogama, Miyagi 985-0001, Japan.
Toxicon. 2001 Dec;39(12):1917-21. doi: 10.1016/s0041-0101(01)00177-5.
Mussels, Mytilus galloprovincialis, were contaminated by paralytic shellfish poisoning (PSP) toxins by being fed with the toxic dinoflagellate Alexandrium tamarense. Temporal variations in the toxin content and the profile of mussels during the feeding experiment were monitored by high-performance liquid chromatography (HPLC). The toxin profile of mussels was compared with that of A. tamarense to clarify the mechanism of uptake of toxins in mussels. The prominent toxins in mussels and A. tamarense were N-sulfocarbamoyl toxins (C1,2) and carbamate toxins, gonyautoxin-1,4 (GTX1,4). The toxin profiles of both mussels and A. tamarense were almost constant throughout the experimental period. There were no remarkable differences in the toxin proportion between mussel and A. tamarense. These results indicate that mussels do not selectively accumulate particular toxins.
贻贝（Mytilus galloprovincialis）通过摄食有毒的甲藻塔玛亚历山大藻（Alexandrium tamarense）而被麻痹性贝类毒素（PSP）污染。在投喂实验期间，通过高效液相色谱法（HPLC）监测贻贝中毒素含量和毒素谱的时间变化。将贻贝的毒素谱与塔玛亚历山大藻的毒素谱进行比较，以阐明贻贝摄取毒素的机制。贻贝和塔玛亚历山大藻中的主要毒素是N-磺基氨基甲酰毒素（C1,2）和氨基甲酸酯毒素，即膝沟藻毒素-1,4（GTX1,4）。在整个实验期间，贻贝和塔玛亚历山大藻的毒素谱几乎保持不变。贻贝和塔玛亚历山大藻之间的毒素比例没有显著差异。这些结果表明，贻贝不会选择性地积累特定毒素。
