氨基糖苷类-链丝菌素抗性基因簇aadE-sat4-aphA-3在粪肠球菌多重耐药菌株中传播。
Aminoglycoside-streptothricin resistance gene cluster aadE-sat4-aphA-3 disseminated among multiresistant isolates of Enterococcus faecium.
作者信息
Werner G, Hildebrandt B, Witte W
机构信息
Wernigerode Branch, Robert Koch-Institute, 38855 Wernigerode, Germany.
出版信息
Antimicrob Agents Chemother. 2001 Nov;45(11):3267-9. doi: 10.1128/AAC.45.11.3267-3269.2001.
Abstract
Seventy-two Enterococcus faecium isolates of different origins highly resistant to nourseothricin and streptomycin were studied. Sequencing of a genomic fragment from two isolates identified a gene cluster, aadE-sat4-aphA-3, which has been isolated recently in staphylococci and Campylobacter coli. Patterns of digested PCR products of aadE-sat4-aphA-3 were identical for all isolates.
摘要
对72株来自不同来源、对制霉菌素和链霉素高度耐药的屎肠球菌分离株进行了研究。对两株分离株的一个基因组片段进行测序，鉴定出一个基因簇aadE-sat4-aphA-3，该基因簇最近在葡萄球菌和大肠弯曲菌中被分离出来。所有分离株的aadE-sat4-aphA-3的PCR消化产物模式均相同。
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