van den Brand I C, Castelein R M
Department of Orthopaedic Surgery, Isala Clinics, Weezenlanden, Zwolle, The Netherlands.
J Arthroplasty. 2001 Oct;16(7):850-5. doi: 10.1054/arth.2001.25547.
This study examined the difference in postoperative bacteriuria in total joint arthroplasty after use of either an indwelling catheter or intermittent catheterization. Previous studies showed a preference for an indwelling catheter over intermittent catheterization to resolve postoperative urinary retention in total joint arthroplasty, but these studies generally used 48 hours of antibiotic prophylaxis. Increasing awareness of costs and bacterial resistance to antibiotics have prompted many centers to reduce prophylaxis to only 1 preoperative dose A prospective, randomized, controlled trial was conducted in primary total hip and primary total knee arthroplasty patients. One dose of cefazolin, 1 g, was administered intravenously immediately preoperatively. Five of 13 (38%) men in the indwelling catheter group and 0 of 14 (0%) men in the intermittent catheterization group developed postoperative bacteriuria (P =.016), and 6 of 33 (18%) women in the indwelling catheter group and 3 of 39 (8%) women in the intermittent catheterization group developed postoperative bacteriuria (not significant). A total of 11 (24%) patients in the indwelling catheter group (n = 46) and 3 (6%) patients in the intermittent catheterization group (n = 53) developed postoperative bacteriuria (P =.018). In this setting with 1-dose antibiotic prophylaxis, intermittent catheterization resulted in a lower incidence of postoperative bacteriuria compared with an indwelling catheter. For men, this difference is significant.
本研究探讨了在全关节置换术中使用留置导尿管或间歇性导尿术后菌尿的差异。既往研究显示,在全关节置换术中,相较于间歇性导尿,更倾向于使用留置导尿管来解决术后尿潴留问题,但这些研究一般使用48小时的抗生素预防。随着对成本意识的提高以及细菌对抗生素耐药性的增加,许多中心已将预防措施减少至仅术前一剂。在初次全髋关节置换术和初次全膝关节置换术患者中进行了一项前瞻性、随机对照试验。术前立即静脉注射一剂1g头孢唑林。留置导尿管组13名男性中有5名(38%)发生术后菌尿,间歇性导尿组14名男性中无一人(0%)发生术后菌尿(P = 0.016);留置导尿管组33名女性中有6名(18%)发生术后菌尿,间歇性导尿组39名女性中有3名(8%)发生术后菌尿(无统计学意义)。留置导尿管组(n = 46)共有11名(24%)患者发生术后菌尿,间歇性导尿组(n = 53)有3名(6%)患者发生术后菌尿(P = 0.018)。在这种采用一剂抗生素预防的情况下,与留置导尿管相比,间歇性导尿导致术后菌尿的发生率更低。对于男性而言,这种差异具有统计学意义。