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与啮齿动物细胞中含多聚腺苷酸(poly(A))的RNA相关的4.5S RNA系列。

Series of 4.5S RNAs associated with poly(A)-containing RNAs of rodent cells.

作者信息

Harada F, Kato N, Hoshino H

出版信息

Nucleic Acids Res. 1979 Oct 25;7(4):909-17. doi: 10.1093/nar/7.4.909.

Abstract

Uninfected mouse kidney cells and mouse leukemia cells L1210 in cluture contained a series of 4.5S RNAs which was structurally identical to the series of 4.5S RNAs associated with genomic RNAs of murine retroviruses and poly(A)-containing RNAs from virus infected cells. Normal rat kidney cells and baby hamster kidney cells in culture also contained a series of 4.5S RNAs. The strucutre of the 4.5S RNAs from mouse, rat and hamster cells were very similar, but not identical. These 4.5S RNAs were not found in cultured cells of other vertebrates, such as human, monkey, cat, mink, rabbit and chicken cells.

摘要

未感染的小鼠肾细胞和培养中的小鼠白血病细胞L1210含有一系列4.5S RNA,其结构与与鼠逆转录病毒基因组RNA以及病毒感染细胞中含poly(A)的RNA相关的4.5S RNA系列相同。培养中的正常大鼠肾细胞和幼仓鼠肾细胞也含有一系列4.5S RNA。来自小鼠、大鼠和仓鼠细胞的4.5S RNA结构非常相似,但并不完全相同。在其他脊椎动物的培养细胞中未发现这些4.5S RNA,如人、猴、猫、貂、兔和鸡的细胞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c877/342270/9c3c23b97b7c/nar00457-0093-a.jpg

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