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生物粘合剂包裹颅内动脉瘤的早期和晚期结果(作者译)

[Early and late results after coating intracranial aneurysms with biobond (author's transl)].

作者信息

Stöwsand D, Buhl K

出版信息

Acta Neurochir (Wien). 1975;32(1-2):73-82. doi: 10.1007/BF01405904.

Abstract

Fifteen patients with intracranial aneurysms have been treated by coating the aneurysms with Biobond. Three patients died in the postoperative period. Only one patient had recurrent haemorrhage one year after operation. In this case the sac had not been wrapped completely at operation. Histological examination of this aneurysm revealed macrophage reaction and signs of slow disappearance of the plastic. Ten patients, who were followed up for a period of 3 to 8 years after operation, had no recurrent haemorrhage and were in good clinical condition, 8 of them doing full-time work. No complications caused by the material have been encountered. In 5 patients carotid angiography was performed after operation. In 2 cases the size of the aneurysm was diminished and in 3 cases was unchanged. There were no signs of thrombosis or narrowing of the adjacent arteries. We believe that Biobond is suitable for coating intracranial aneurysms that cannot be treated by clipping or ligature. As Biobond in vivo seems partially to disappear after long periods, it should be applied in thick layers.

摘要

15例颅内动脉瘤患者接受了用生物胶包裹动脉瘤的治疗。3例患者在术后死亡。仅1例患者在术后1年出现复发性出血。该病例中,手术时瘤囊未完全包裹。对该动脉瘤进行组织学检查发现有巨噬细胞反应以及塑料缓慢消失的迹象。10例患者术后随访3至8年,无复发性出血,临床状况良好,其中8例从事全职工作。未遇到由该材料引起的并发症。5例患者术后进行了颈动脉血管造影。2例动脉瘤大小减小,3例未变。未见血栓形成迹象或邻近动脉狭窄。我们认为生物胶适用于包裹无法通过夹闭或结扎治疗的颅内动脉瘤。由于生物胶在体内长时间后似乎会部分消失,因此应厚层应用。

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