Hattori A
Fujisawa Pharmaceutical Co., Ltd., Osaka.
Yakushigaku Zasshi. 1992;27(2):78-82.
In the Edo Period a packaging insert for a patent medicine had two characters; the one was instructive and the other was advertising for taking a medicine. As there was not enough space in packaging for a patent medicine at thet time to describe the instruction for the medicine, history of the medicine, indication, how to take it, etc., they were shown on the back of the wrapping paper. Though some packaging inserts described volubly the merit of their medicines, most of them did not. It was influenced by a writer of the packaging insert.